MealShape®

The next generation carb blocker

What is MealShape® ?

An innovative starch blocker clinically-proven to instantly block carb absorption by more than 20%.

By inhibiting enzymatic digestion of dietary starch, MealShape® helps prevent glycemic spikes and sugar crashes, thus aiding the body to reduce the conversion of excess sugar into fat.

A carb blocker to be easily incorporated and formulated into products for human and animal nutrition

  • Dietary supplements
  • Functional food
  • Functional beverages

Scroll over below pictures to find out more about MealShape® possibilities !

Je suis une transition entre le paragraphe MealShape carb blocker et le paragraphe ceylon cinnamon extract. 

The first and only Ceylon cinnamon extract working as a carb blocker

MealShape® is a unique Ceylon cinnamon extract with carb blocking properties. Using the safest cinnamon species along with a specific extraction process, Dialpha developed and patented a 100% natural Ceylon cinnamon extract demonstrating high biological efficacy.
MealShape® is a food-grade extract with standard polyphenols content ≥ 40%.

Ceylon cinnamon, the safe species

Ceylon cinnamon, commonly named “the true cinnamon” is one of the 2 common cinnamon species next to cassia cinnamon. A notable difference between the 2 species is their coumarin content. Coumarin is a potentially natural harmful molecule which may pose health risks if consumed excessively (anticoagulant properties). Ceylon cinnamon only contains traces of coumarin and is entirely safe for consumption whereas cassia cinnamon contains higher levels of coumarin and may present risks to individuals if consumed in significant quantities on a regular basis.

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How does it work?

Today’s lifestyle and its consequences

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Carbohydrates constitute 45 to 60% of our daily food intake. They are essential to the body as they are the main source of energy. However, an excessive consumption of highly refined carbs with a high Glycemic Index* can lead to obesity and type 2 diabetes.

*What is the Glycemic Index (GI)?

The GI is a scale that ranks carbohydrate-rich foods by how much they raise blood glucose levels compared to standard food (for glucose, the GI = 100). It is an indicator that can help manage weight and blood sugar levels.

MealShape® along with a healthy diet makes you feel better overall. It helps your body to maintain an optimal weight and to lower your risks of metabolic disorders including diabetes, high cholesterol level and cardiovascular diseases.

Reduction of postprandial glycemia

MealShape® reduces the postprandial glycemia induced by a starchy meal, without stimulating insulin secretion :

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MealShape® also limits the reactive hypoglycemia observed after high glycemic index food intake, thus promoting beneficial effects on satiety.

MealShape® global benefits

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Various studies have shown that low glycemic index diets improve blood glucose control and insulin sensitivity, manage cholesterol, and are associated with reduced risks for developing obesity and cardiovascular diseases.

References:
International Diabetes Federation. Guideline for management of postmeal glucose in diabetes. 2011.
McMillan et al. Comparison of 4 diets of varying glycemic load on weight loss and cardiovascular risk reduction in overweight and obese young adults: a randomized controlled trial. Arch intern Med. 2006.
Hanefeld et al. Postprandial plasma glucose is an independent risk factor for increased carotid intima-media thickness in non-diabetic individuals. Atherosclerosis. 1999.
Opperman et al. Meta-analysis of the health effects of using the glycaemic index in meal-planning. Br J Nutr. 2004.
Ceriello et al. Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin treatment. Diabetes. 2004.

Published human clinical data

Post-meal blood glucose decreased by more than 20% with MealShape®

After multiple preclinical trials showing a strong and consistent efficacy on postprandial glycemia, MealShape® was studied in a randomized, cross-over, double-blind, and placebo-controlled trial1. Healthy female and male volunteers were given MealShape® or a placebo (2 capsules of 500 mg) before eating a standard meal (white bread) after an overnight fast. Glycemia and insulinemia were measured over 2 hours after bread consumption.

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MealShape® significantly reduced glycemia by more than 20% after a meal without stimulating insulin secretion.
*p<0.05 on Area Under the Curve between 0 and 60 minutes

MealShape® was well tolerated as no side effects appeared during the study. The ingredient may be of interest for people looking for natural solutions to manage post-meal blood glucose and body weight without side effects.

1Reference: Beejmohun et al. BMC Complement Altern Med., 2014
http://www.biomedcentral.com/1472-6882/14/351

Mechanism of action

MealShape® delays the digestion and the absorption of carbohydrates by inhibiting alpha-amylase activity. This pancreatic enzyme breaks down starch into sugars which are absorbed by the organism.

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Proof of concept in bread

MealShape® was incorporated and cooked in a French baguette. The effect on postprandial glycemia was studied in preclinical trials. The results demonstrated a significant dose-related effect: the glycemic index of bread containing 0.5% MealShape® significantly decreased by 30%.

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MealShape® has the property to lower the Glycemic Index of starchy foods. This can support consumers to follow a low GI diet for a better control of blood sugar and body weight.

The health claims have not been evaluated by regulatory authorities. This product is not intended to diagnose, treat, cure, or prevent any disease.
Companies intending to distribute the ingredient or market end products containing the ingredient should make sure that all claims comply with the current regulations of the country they operate in.

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